| 1436 |
Leon Battista Alberti publishes On Painting |
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Piero della Francesca(ca. 1412–1492) |
| 1450 |
Pope Nicholas V founds Vatican Library |
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Andrea Mantegna (ca. 1430–1506) |
| 1453 |
Turkish invaders capture Constantinople |
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Marsilio Ficino (1433–1499) |
| ca. 1454 |
Johann Gutenberg prints Bible |
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Sandro Botticelli (ca. 1444–1510) |
| 1464 |
First printing press in Italy |
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| 1469 |
Marriage of Ferdinand of Aragon to Isabella of Castile unites two Spanish kingdoms |
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Donato Bramante (ca. 1444–1514) |
| 1476 |
First printing press in England |
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| 1478 |
Inquisition established in Spain |
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Pope Julius II (ca. 1445 1513) |
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Sandro Botticelli paints Primavera |
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| 1484 |
Marsilio Ficino publishes translation of Plato's complete works |
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| 1485 |
Henry VII founds Tudor Dynasty in England |
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Lorenzo de' Medici (1449–1492) |
| 1486 |
Giovanni Pico della Mirandola publishes Conclusions, including the introduction now known as Oration on the Dignity of Man |
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| 1487 |
Bartolomeu Dias sails around southern tip of Africa |
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Isabella of Castile (1451–1504) |
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Girolamo Savonarola (1452–1498) |
| 1492 |
Spanish expel Moors from Granada,completing unification of Spain |
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Leonardo da Vinci (1452–1519) |
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Christopher Columbus sails to Americas |
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Holy Roman Emperor Maximilian I (1459–1519) |